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The inclusion criteria were: (1) Study subjects involving human SLE patients (including varying disease activity levels and subtypes such as lupus nephritis) or SLE animal models

It has been demonstrated that when GS is inhibited, a variety of metabolic pathways other than glutamine synthesis are activated, thereby underscoring the remarkable plasticity of cancer cell metabolism

Community sources report a 16-week subcutaneous ladder of 250 mcg daily for Weeks 1-4, 375 mcg daily for Weeks 5-8, and 500 mcg daily for Weeks 9-16, but this is reported research context, not a recommendation

Guo S, Tal R, Jiang H, Yuan T, Liu Y

Apoptosis is characterized by morphological changes that include chromosome shrinkage, chromatin condensation and cytoplasmic fragment formation (2,11)