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doi: 10.17116/jnevro202212211212 57 TurcoL.OpalloN.BuomminoE.De CaroC.PirozziC.Mattace RasoG.et al

These factors collectively portray iron overload as either a causative factor or an outcome of malignancy, irrespective of its source, including unsought iron administrations, ironrich diet, history of chronic diseases or genetic imbalances in ironregulatory system

Nuclear localization of the DAF-16 transcription factor is an indicator of insulin-like signalling, which occurs under stress conditions (Henderson and Johnson, 2001)

Therefore, focusing on mechanisms contributing to cognitive decline in aging and identifying solutions to improve or reverse ACD will (a) have benefits for improving cognitive health in older adults, and (b) could identify potentially viable mechanistic clues for understanding and combating AD and dementia, especially because both aging and AD share several common associations

Studies in neurodegenerative disease models suggest Dihexa's regenerative capabilities extend to reversing existing damage rather than merely preventing further deterioration