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Astroglial atrophy in Alzheimer's disease

CrossRef The protective effects of sulforaphane on high-fat diet-induced metabolic associated fatty liver disease in mice via mediating the FXR/LXR pathway Shaotong Ma, Xinyi Pang, Shuhua Tian, Jing Sun, Qiaobin Hu, Xiangfei Li, Yingjian Lu Food & Function.2022

Targeted Pathway Support: Add-on therapies layered onto baseline therapy when symptoms suggest involvement of specific mediator pathways (e.g., leukotrienes or serotonin)

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As shown in Figure 2D, convulxin and collagen induced NOXs activation and degraded NADPH, and the absorbance value at 450 nm was increased compared with non-activated human platelets, and NOXs inhibitor (VAS2870) and luteolin significantly decreased the convulxin- and collagen induced NOXs activity