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When mTOR is inhibited under hypoxic or low-calorie conditions (as happens in endurance exercise), it promotes stem cell mainenance and regenerative capabilities

Some studies suggest that individuals with low levels of B12 are more prone to developing age-related cognitive decline and that supplementation can slow down or even reverse certain symptoms of mental impairment

Benowitz NL, Jacob P3, Mayan H, Denaro C (1995) Sympathomimetic effects of paraxanthine and caffeine in humans

(2009) found that mutation of a Gpx to exchange the selenocysteine to cysteine at the catalytic site reduced the specific activity of the enzyme by two to three orders of magnitude

You can read more in our guide on how long it takes for B12 injections to work