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Additionally, ROS activate pro-apoptotic signaling molecules such as apoptosis signal-regulating kinase 1 (ASK1), c-Jun N-terminal kinase (JNK), and p38 [37]

To better characterise the antioxidant profile resulting from VACV infection, the activities of the endogenous antioxidant enzymes SOD, CAT, and GPx were measured

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CMP-001, also named as Vidutolimod, is a short DNA piece packaged in protein, mimicking the virus structure

Jain, et al., 1999), we showed that both prokaryotes and eukaryotes contain two types of genes, and both types have different inheritances