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Melanoma is devastating but potentially preventable

Second, as mentioned above, c-Met inhibitors which target the interaction between HGF and c-Met may lose efficacy owing to cell attachment (Wang et al., 2001), gene amplification of c-Met, DCP binding to c-Met (Suzuki et al., 2005), gene mutation in the c-Met activation loop (Okuma and Kondo, 2016) and crosstalk with other membrane receptors (Garcia-Vilas and Medina, 2018)

SIRT3 is a mitochondria-localized NAD-dependent deacetylase that regulates cellular metabolism and homeostasis 13

Zhang Z, Liu R, Shuai Y, Huang Y, Jin R, Wang X, Luo J (2020) ASCT2 (SLC1A5)-dependent glutamine uptake is involved in the progression of head and neck squamous cell carcinoma

Nazari L, Salehpour S, Hosseini S, Allameh F, Jahanmardi F, Azizi E, et al