glutathione plays an important role in reducing intestinal inflammation Gut microbiota-related metabolism is key mechanism for sulforaphane ameliorating ulcerative colitis Impairment of intestinal glutathione synthesis

[U-13C] Glucose labelling showed less glucose-derived carbon entering the tricarboxylic acid (TCA) cycle

Ggt1, which is expressed at high levels in renal proximal tubules, is considered the central enzyme that maintains the systemic redox balance by hydrolyzing glutathione to glutamate and Cys-Gly via the glutathione pathway

3 Thus, in general, ferroptosis is regulated mostly by lipid metabolism, iron homeostasis, and redox system homeostasis

Torres-Vega et al., 2012) the reader is referred to the specialized reviews

ROS and RNS (Reactive Nitrogen Species) caused damages can be prevented and repaired by free radical scavengers, which are the exogenous and endogenous antioxidants, and thereby, the immune defense will get enhanced and the risk of getting cancer and degenerative diseases gets lowered (Pham-Huy, He, & Pham-Huy, 2008)