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The authors underlined that this could be mediated by the reduction in caspase-3/7 activity, by the increase in the B-cell lymphoma 2/BCL-2-like protein 4 (BCL2/BAX) ratio and by the reduction in tumor protein 53 (TP53), caspase-3 (CASP3) and caspase-8 (CASP8) expression [82]

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Acknowledgements We gratefully acknowledge ChemAxon for providing us with an academic license for their software

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