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Mitochondrial involvement is suggested by ex-vivo studies (Czerniczyniec et al., 2013, 2015)

Consistent with our historical methodology, to determine the applicable area wage index values for the FY 2024 LTCH PPS standard Federal payment rate, under the broad authority of section 123 of the BBRA, as amended by section 307(b) of the BIPA, we are proposing to continue to employ our historical practice of using the same data we are proposing to use to compute the proposed FY 2024 acute care hospital inpatient wage index, as discussed in section III

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gingivalis LPS) significantly downregulated both the transcription and protein expression of SLC7A11 via the TLR4/NF-B pathway, inhibiting cystine uptake, leading to insufficient GSH synthesis and loss of GPX4 activity (40), thereby directly impairing cellular antioxidant capacity