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doi: 10.1038/s41401-020-0358-x 184 MatheoudDSugiuraABellemare-PelletierALaplanteARondeauCChemaliMet al

Many newly developed DUB inhibitors, such as Novartis's CSN5i-3 (102) or the already marketed drug pimozide (103), have been found to exhibit significant functions in the field of cancer therapy

19 Thus, characteristics of HIV-1 including a higher viral load, greater pathogenicity, and the ability to escape neutralization more often, contribute to its widespread prevalence