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Impaired epithelial integrity leads to intestinal barrier dysfunction Recent studies have shown that the disruption of intestinal barrier integrity is not only a consequence of IBD but may also be a key driving factor in the onset and progression of the disease

Both glutamate receptor degradation and an increase in glutamate secretion levels can cause this abnormality

S., Quinolone Antimicrobial Agents, 2nd ed, 59 - 75, 1993

Caution is advised in patients with existing medical conditions, and dosage adjustments might be necessary

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