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Despite substantial glutathione deficits, the mice are outwardly healthy

Marburg multiple sclerosis variant: Complete remission with very early administration of mitoxantrone-a case report

On the other hand, endoplasmic reticulum stress can promote cell ferroptosis and may be involved in the co-regulation of ferroptosis and apoptosis [61]

In vitro studies using normal human epidermal keratinocytes revealed that treatment with glutathione amino acid precursors significantly increased both GSH and glutathione disulfide levels, leading to an improved GSH/glutathione disulfide ratio, which is a key indicator of cellular redox balance