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Description

Pharmacological prevention of eNOS uncoupling Understanding the mechanisms and the importance of eNOS uncoupling as a one of major causes of endothelial dysfunction has made reversing or preventing eNOS uncoupling an attractive therapeutic approach to prevent or treat cardiovascular complications

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The observations reported herein show that pro-GSH molecules represent new therapeutic agents to support immune modulation. [222] These data indicate that glutathione peroxidase-dependent control of intracellular reactive oxygen species accumulation is important not only for regulation of TH-cell proliferation, but also for modulation of differentiation into TH1, TH2 and TH17 cells.[223] See the clinical strategies described above for strategies for increasing glutathione levels

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