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Furthermore, actively cycling CAR T cells isolated from a patient with a decade-long leukemia remission showed upregulation in LDHA and OXPHOS pathways, suggesting that both aerobic glycolysis and mitochondrial respiration are increased in CAR T cells that persist long-term 25

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Carotenoids are incredibly powerful antioxidants and are known as the most potent physical quencher of singlet oxygen [164]