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Although human trials with dietary antioxidants have failed to reduce disease outcomes, it is important to recognize that these interventions are less efficacious in reducing oxLDL levels in humans than in rodent models

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The accumulation of toxic substances leads to oxidative damage to cells and a decrease in Na + -K + -ATPase activity, which results in the activation of NMDA receptors, neuronal depolarization, and clinical symptoms such as seizures

Treatment also decreased the expression of BAX, caspase 3, OX42 and ED1 after 2 weeks

J Gastroenterol Hepatol 29:14491457 Hozo SP, Djulbegovic B, Hozo I (2005) Estimating the mean and variance from the median, range, and the size of a sample