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Peptides, such as BPC157, have patent issues due to the ability to modify them by adding one amino acid, making them a different compound, which is a problem with patent laws for peptides 10s

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However, in a controversial study, CHAC1 was identified as a uniquely downregulated gene in rhabdomyosarcoma (RMS) tumors treated with the combination therapy of low-dose vincristine (VCR) and FOXM1 inhibitor RCM1, delivered via nanoparticles