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This on/off cycle was repeated 5 times, with the temperature differentials of the solution continuously recorded throughout

During hypoxia or mitochondrial dysfunction, KG can be converted to citrate in an IDH2-catalyzed reductive carboxylation reaction

Given the rich lipid content of the nervous system, hemoglobin-derived iron works with lipid peroxidation to induce ferroptosis, which eventually leads to neuronal mitochondrial damage, edema, and apoptosis of neurons and astrocytes

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CysLT1 Receptor Antagonist Alleviates Pathogenesis of Collagen-Induced Arthritis Mouse Model