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There is no human side-effect dataset

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Shaking also creates foam, which dramatically increases the surface area exposed to air and can physically denature proteins and larger peptides through the mechanical forces at bubble interfaces

the first coating may further comprise, in addition to the copolymer (A), one or more polymers selected from ethyl cellulose, hydroxypropyl methylcellulose (HPMC), and polyvinyl acetate

All three are prohibited by WADA in category S2 as growth hormone secretagogues and are also banned in the MLB and NFL