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In the salvage pathway, DHFR exhibits a critical role in BH4 generation

ALOXE3, arachidonate lipoxygenase 3

Individualized dosing of tyrosine kinase inhibitors: are we there yet

10.3892/etm.2020.9264 160 YanF.ZhaoQ.LiY.ZhengZ.KongX.ShuC.et al (2022)

For acute injury models, daily dosing is common for the first 7-14 days, transitioning to less frequent administration as the recovery window progresses