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the likelihood that the disease course, pathophysiology, and the drugs effect in pediatric and adult patients are substantially similar

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Data from 22 separate published studies that included 680 research participants were included in the analysis

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Fatty acid metabolism to buffer against cisplatin stress Fatty acid metabolism is an integral component of cancer cell physiology and plays pleiotropic roles, ranging from membrane biosynthesis and signaling intermediates to biomass production, energy generation, and posttranslational modification [113]