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Expression was assessed by transcriptomics (RNA-seq)

PMID 30940813

Experimental studies in rodents and other small mammals consistently demonstrate that disruptions to normal light-dark cycles (e.g., via phase shifts, continuous light or darkness, or dim LAN) can impair various components of the immune system, including natural killer (NK) cell activity, cytokine production, balance in white blood cell populations, and immune responses to pathogens, tumors, or injury 87

Epidermal fatty acid binding protein (E-FABP) expression in nave CD8+ T cells facilitates linoleic acid transport via mitochondria and its incorporation into cardiolipin, which induces lipid peroxidation and mitochondrial ROS production, leading to apoptosis and reduced TNF production [84]

doi: 10.1186/1742-2094-8-63 92 PatelM