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Just as booster mRNA-1273 stimulated nAb [neutralizing antibody] levels against the original strain, a booster injection of mRNA-1273 was able to broaden and increase nAb levels against the Delta variant, highlighting the critical benefits of mRNA-1273 booster dose . The authors of the current study suggest that this route could result in long-term vaccine efficacy and a return to neutralizing capacity against multiple circulating and newly emerging variants

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Subsequent development as an obesity drug was discontinued due to the small effect size, though research continues on its potential role in cartilage repair and localized metabolic applications