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Cocoa supplementation can also lower CD68 + neutrophils, MPO, TNF-, IL-1 and IL-17 and suppress STAT-3 activation in colitic tissues (204) ( Supplementary Table 1 )

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There are currently ongoing observational studies and early-phase clinical investigations of BPC-157 in gastrointestinal disease, reflecting the strength of the gut healing literature and the relative accessibility of GI endpoints in human trials

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