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The major stages of lung development, going from a glandular structure to an alveolar structure capable of efficient gaseous exchange with the capillary network, begin at the eighth week of gestation and continue to term (40 weeks) and postnatally [5]

Moreover, it suggests that in these lineages SVCTP has a dedicated function, such as VC transport, rather than a generalized function, since the loss of a gene performing multiple functions is likely lethal

Mitochondrial damage is considered the main generator of intracellular pathologic levels of O 2 - through NADPH oxidase, which originates in neutrophils, eosinophils, monocytes, and macrophages [85-88]

The standard regimen is 1mg injections three times weekly for two weeks, followed by maintenance doses of 1mg every 2-3 months