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Ferroptotic cancer cells are more likely to provoke tumor-specific immune responses, enhancing the efficacy of immune checkpoint inhibitors (ICIs) (80,81)

Community protocols describe a 50 mg/day starting phase lasting 1-2 weeks, escalating to 100-150 mg/day based on tolerance

Edaravone attenuates the proinflammatory response in Amyloid--Treated Microglia by inhibiting NLRP3 inflammasome-mediated IL-1 Secretion

At the level of ferroptosis, hypoxia inhibits lipid peroxidation through a dual mechanism: 1) HIF-1/2 upregulates PLIN2, a lipid droplet-associated protein, forming a physical barrier to isolate peroxidation reaction substrates (Zou et al., 2020) (215)

thaliana resistant and susceptible to R