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Necrosis caused by C

[DOI] [PubMed] [Google Scholar] 35.Ganguli M, Chandra V, Kamboh MI, Johnston JM, Dodge HH, Thelma BK, Juyal RC, Pandav R, Belle SH, and DeKosky ST

10.3390/antiox13050573 52 MoirH

The absence or diminished function of ATP7B results in accumulation of copper in the hepatocyte due to both impaired copper excretion into bile and inability to incorporate copper into ceruloplasmin.14 The production of ceruloplasmin without attached copper (apoceruloplasmin), which has a shorter half-life than ceruloplasmin, results in decreased levels of ceruloplasmin in the blood of Wilsons patients