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Only for antioxidant purposes, the body will recycle the glutathione itself

Glutathione helps protect our cells and tissues from damage caused by harmful free radicals

Consequently, a vicious cycle of mutual exacerbation is formed among copper dyshomeostasis, autophagic dysfunction, myocardial lipotoxicity, and mitochondrial injury, which collectively drives the pathological progression of cardiomyocyte damage and contractile dysfunction in SCM

However, the electron transport chain (ETC) is considered the primary source of ROS, being solely responsible for the production of approximately 90% of the total cellular ROS

Farez MF, Mascanfroni ID, Mndez-Huergo SP et al (2015) Melatonin contributes to the seasonality of multiple sclerosis relapses