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According to the applicant, the TOPS TM System received Breakthrough Device designation from FDA on October 26, 2020 for patients between 35 and 80 years of age suffering from neurogenic claudication resulting from degenerative spondylolisthesis up to Grade I with moderate to severe lumbar spinal stenosis and either the thickening of the ligamentum flavum or scaring facet joint capsule at one level from L2 to L5

She is known for bringing structure to complexity, aligning stakeholders, and removing barriers so teams can focus on delivering the companys most critical initiatives

however, the reduction occurred earlier in OGTT and was delayed in IPGTT, consistent with prior studies

10.1002/iub.2463 254 ZhangL.YangY.LiY.WangC.BianC.WangH.et al (2025)

Higher activity of mitochondrial ATP synthase (depending on tumor type) can be associated with higher metastatic activity 40