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Combined respiratory chain deficiency and UQCC2 mutations in neonatal Encephalomyopathy: defective Supercomplex assembly in complex III deficiencies

Although the exact cause of AD remains elusive, it is understood to involve a complex interplay of genetic predisposition, environmental influences, lifestyle factors, and dietary habits [17]

Exposure of aSyn to nitrating agents can encourage o,o-dityrosine crosslinking between the N-domain tyrosine (Y39) and C-terminal tyrosines (Y125, Y133, Y136) to generate aSyn-dimers that are more prone to oligomer formation 105,106,107,108

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