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Demand is not a surrogate for safety. Verbois suggests that the PCACs evaluation and the FDAs ultimate decision on the seven peptides must account for how these products are being marketed and sold in the real world

Effect of dose of hypertonic saline on its potential to prevent lung tissue damage in a mouse model of hemorrhagic shock

Thus we still have to be aware of the potential limitations as well as we have to bear in mind that the apparent diagnostic performance of a biomarker depends not only on its ability to detect injury, but also on disease prevalence and the sensitivity and specificity of the imperfect gold standard 25

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doi: 10.1038/s41586-020-2456-9 231 Robledinos-AntnN.Fernndez-GinsR.MandaG.CuadradoA