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ACSL catalyzes FAs with 10 to 22 carbons and is composed of five isoenzymes, including ACSL1, ACSL3, ACSL4, ACSL5, and ACSL6

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found out that incubation of HUVECs with HG media promotes the generation of endothelial microparticles (EMPs) that, when added to normally cultured HUVECs, downregulate the expression of anti-apoptotic microRNA miR-Let7a, but enhance the synthesis of active caspase-3 and cause cell apoptosis (53)

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