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Mol Pharmacol 69:1182-1193, 2006

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Chlorophylls, nonetheless, exert potent reactive oxygen species scavenging effects, as described in detail for chlorophyllin, a water-soluble analog of chlorophylls.17 Since the cell proliferation is strongly influenced by redox signaling,18 this antioxidant action of chlorophylls might account for their presumed anti-proliferative properties

12.0 12.1 Puri, B K

Reduced FH enzyme activity leads to the accumulation of the cellular level of fumarate, and fumarate can undergo a reaction with cysteine residues of proteins, which is called succination (Pollard et al., 2005)