glutathione reaction product Schematic chemical of the Total Assay (adapted Modelling changes in glutathione homeostasis

N-acetylcysteine, or NAC, is a supplement that works in two ways: It provides cysteine, which is the rate-limiting amino acid for glutathione production It can also act as a direct antioxidant to scavenge ROS (NO2 and HOX)[ref][ref] The main antioxidant mechanism for NAC is by increasing glutathione levels

10.1080/10408360500523878 Crit Rev Clin Lab Sci

It is available as a dietary supplement and medication for various health conditions

The reactive SH group of glutathione can form a thioether by reacting with C=C double bonds, carbonyl groups or other reactive groups forming a glutathione conjugate

doi:10.1016/j.freeradbiomed.2011.04.013