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The increase in the incidence of metabolic syndrome probably decreases the accuracy of risk prediction for CAD events when LDL-C is used for that purpose, whereas non-HDL-C, total apo B concentration, and LDL particle concentration retain predictive capability in this patient population

Notably, mannose, a key sugar molecule, serves as a targeting agent for BSCB transport, enabled by its mannose receptor (MR), which is extensively expressed in immune cells and endothelial cells of the nervous system

However, data obtained from these studies were either contradicting or inconclusive

Accessed 9/9/15