Since proliferating cells in the colon are present in the lower part of the crypt, this may determine that these cells are supposed to be the main targeted cells in case of colon carcinogenesis Progenitors or stem cells are very sensitive towards the redox environment
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In secondary hypothyroidism Either, insufficient TSH is produced, and thus the thyroid gland does not produce sufficient T3 and T4 Or, the thyroid gland has been removed or damaged surgically, or by radiotherapy or another process, and thus is unable to produce sufficient T3 and T4 It is crucial to understand this process to be able to interpret thyroid function test blood results
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