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The net effect: in serum or in cell culture media containing serum, free IGF-1 is rapidly bound and sequestered

Full-length thymosin beta-4, formulated as a topical ophthalmic solution (RGN-259), has been evaluated in genuine Phase II randomized, placebo-controlled human trials for dry eye disease

Tesofensine , a triple monoamine reuptake inhibitor, showed significant weight loss in Phase 2 trials through appetite suppression and increased metabolic rate

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