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Defects in the AR gene can prevent the normal development of both internal and external male structures in 46, XY individuals and result in androgen insensitivity syndrome, which is the partial or complete inability of cells to respond to androgens 13,101,102

The entorhinal cortex is the primary brain region to be affected in Alzheimer's disease 21

The cancer can also invade nerves, blood vessels, and lymphatics within the pancreas

Subsequently, Nrf2 accumulates and translocates to the nucleus, where it binds to the Antioxidant Response Element (ARE), initiating the transcription of a battery of cytoprotective genes responsible for counteracting inflammation and oxidative stress

At the outer mitochondrial membrane, an enzyme called Carnitine Palmitoyltransferase 1 (CPT1) attaches the fatty acid to a molecule of L-Carnitine, creating acylcarnitine