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10.7150/ijbs.105667 122 XiaoL.XuX.ZhangF.WangM.XuY.TangD.et al (2017)

The crystals can also be broken down in the body (see 7a below, re: Rasburicase, and 7b below, re: pegylated uricase)

For lactate quantitation, samples (5 L, run in triplicate) were added to 115 L assay buffer containing 100 mM glycylglycine, 100 mM glutamate, 2 mM NAD, 1 U/mL lactate dehydrogenase, and 1 U/mL glutamate pyruvate transaminase, pH 8.5