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Their anti-tumor activity depends on Fc-dependent immune effector mechanisms and immunomodulatory effects that eliminate CD38 regulatory T cells and restore T-cell- and NK-cell-mediated antitumor immune responses [56]

"Adipocyte apoptosis: a novel target for obesity therapy." Experimental & Molecular Medicine 52 (2020): 1039-1051

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Indeed, the SELECT trial demonstrated that semaglutide reduced major adverse cardiovascular events (MACE) by 20% despite the modest heart rate increase

J.FastW.WeerapanaE.et al (2019)