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Forty-six patients (32 with AK and 14 with BD), aged 31 to 91 years, were included

2.1 Blood-brain barrier regulation The BBB is mainly composed of brain microvascular endothelial cells and their intercellular tight junctions, intact basement membranes, pericytes, and astrocytes, of which the endothelium is the main structure

Supplements may interact with other medications or exacerbate certain medical conditions

Despite the described interplay among oxidative stress, vitamin D deficiency, and obesity, the investigation of the potential therapeutic role of vitamin D in modulating redox homeostasis in the varicose veins has been less addressed in the literature

Furthermore, the acetylcarnitine supplementation has been reported to be as effective as antidepressants in meta-analyses [64, 143]