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Lysosomal cystine levels were regulated by the major facilitator superfamily domain containing 12 (MFSD12)-mediated import and the lysosomal cystine transporter (CTNS)-mediated efflux and were sensed by the AhR-kynurenine pathway [41,42,43]

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Ernst, L

When the cell is exposed to stimuli such as various growth factors, cytokines, hormones or bacterial components (such as fMetLeuPhe), the subsequent activation of various isoforms of protein kinase C leads to phosphorylation of the cytosolic component p47 phox , which, along with p67 phox and p40 phox , interacts with the flavocytochrome b 558 at the membrane