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Usually, the cell can remove reactive oxygen species (ROS) and reactive nitrogen species (RNS) through antioxidant molecules such as reduced glutathione (GSH) and primary defense enzymes such as superoxide dismutase (SOD), catalase (CAT), and glutathione-dependent peroxidases (GPx) [1]

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One week post-injection, mice were placed on a MASH-inducing diet enriched in fat, cholesterol and fructose (TD160785, Envigo) for 13 weeks

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