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Many identified metabolites, such as those containing sulfur and phenol, are known to be toxic to enterocytes, disrupt intercellular tight junctions (TJ), and stimulate bacterial translocation, all of which support this idea (Cox et al., 2014)

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The change in diet should begin with a waiting period, then move on to a test phase and end with an individually designed long-term diet

As implied by the synonym, chronic hepatic encephalopathy occurs in the setting of portosystemic shunting, usually as a result of cirrhosis