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the peptide has the potential to induce a wide range of responses from growth stimulation to toxic cell differentiation

Proc Natl Acad Sci USA 100(8):48794884

doi: 10.1002/glia.20557 50 CooperMLPasiniSLambertWSD'alessandroKBYaoVRisnerMLet al

The brain is particularly susceptible to OS due to high metabolism required to maintain synaptic activity, and increased OS is associated with AD and MCI