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Emerging evidence shows that soybean -CG causes intestinal abnormalities, including inflammation 6 , oxidative stress 7 , mucosal barrier dysfunction 8 , defects of nutrient absorption 9 , and enterocyte damage 10

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Accordingly, a pharmaceutical composition refers to compositions exhibiting prophylactic and/or therapeutic activities

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Therefore, therapeutic targets for improving astrocytic function include enhancement of IGFR signalling and mitochondrial function and glucose transport, which can alleviate age-related pathologies such as AD (Fig