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This timing allows the compound to activate the PPAR-delta pathway, optimizing fat metabolism and energy utilization during exercise, leading to better performance and stamina

Compared to WT controls, 5xFAD mice exhibited reduced fEPSP responses across a range of stimulus intensities, indicating impaired basal synaptic transmission

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At the end of the study the mice were euthanized, and the livers were collected and quickly washed twice in ice-cold phosphate-buffered saline (PBS)

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