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J Invest Dermatol 133:19791989

Translation of HaSSA transcripts may capture enough synthesized cysteine (for translation and for conversion into methionine for translation) to shortchange other uses of cysteine, such as synthesis of GSH and other antioxidants that are particularly important in the context of accumulated unfolded proteins in the ER and altered redox state in other cellular compartments

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Unlike the DAC-modified version, which binds to serum albumin and remains active for several days, the non-DAC form has a much shorter half-lifemeasured in minutes

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