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Plasmid Construction pGEX-4T-1 was modified with a 6XHis tag in front of a GST tag at the N-terminus, and the thrombin protease cleave sequence was replaced by the TEV protease cleave site by a one-step site-directed deletion and insertion method [59]

As comprehensively discussed in a recent 2025 review, thrombin plays a driving role in the paradoxical interplay between cancer metastasis and the vascular system [296]

Furthermore, to explore the potential therapeutic relevance of modulating lipid metabolism, we administered atorvastatin, a commonly used lipid-lowering drug, to mice with CaOx-induced renal injury

2021 Brain Sciences paper from China Pharmaceutical University and Nanjing First Hospital is the strongest fully independent positive finding identified for this product description