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Description

Leveraging transcriptomic datasets through a pharmacogenomics analysis and developing an expert curation of genes previously involved in oligodendroglial biology (provided as a resource for the scientific community: OligoScore, we identified and ranked small bioactive molecules (compounds) for their capacity to foster transcriptional programs associated with various aspects of oligodendrogenesis, including OPC proliferation, differentiation, and (re)myelination

Noda S, Tanabe S, Suzuki T

Kempin S, Kurland E, Koziner B, Nisce L, Arlin Z, Mertelsmann R, Gee T, Berman E, Andreeff M , Reich L, Clarkson B

Transforming growth factor -1 stimulates profibrotic epithelial signaling to activate pericyte-myofibroblast transition in obstructive kidney fibrosis