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Mechanistically, PM2.5 induces oxidative stress, DNA strand breaks, and aberrant DNA methylation in lung epithelial cells, which together promote genomic instability and malignant transformation [190,191]

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Together with a follow-up study by their group again showing heterogenous glycemic responses to sourdough or white bread [178], these data indicate that often neglected factors such as the microbiome significantly influence the effectiveness of a given dietary intervention